ClinicalKey AI

World class clinical information meets artificial intelligence

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ClinicalKey AI

Ask. Explore. Help elevate patient care.

With unrivaled full-text knowledge base and technology upgrades to help you make clinical decisions with confidence. Save 30% with discount code NXGEN30.

For Clinicians

Free for Students

ClinicalKey AI

Ask. Explore. Help elevate
patient care

Traceable, evidence-based answers at the point of care using leading full-text content from

Elsevier and its partners.

Ask. Explore.
Help elevate
patient care

Traceable, evidence-based answers at the

point of care using leading full-text content

from Elsevier and its partners.

ClinicalKey AI combines trusted, evidence-based clinical content with conversational search powered by generative AI to support clinicians in delivering high-quality patient care.

Transform Complexity into Clarity

With ClinicalKey AI, clinicians can ask questions in a conversational format with AI technology that allows for natural language queries getting an answer in a fraction of the time.

Base decisions on summarized information delivered in bulleted fashion and backed by citations.
Account for patient complexity - including multiple comorbidities and medications - when prompted.
Help strengthen confidence through trusted quality information by accessing evidence-based content curated by Elsevier's expansive network of domain experts.

Transform Complexity into Clarity

With ClinicalKey AI, clinicians can ask questions in a conversational format with AI technology that allows for natural language queries getting an answer in a fraction of the time.

Base decisions on summarized information delivered in bulleted fashion and backed by citations.
Account for patient complexity - including multiple comorbidities and medications - when prompted.
Help strengthen confidence through trusted quality information by accessing evidence-based content curated by Elsevier's expansive network of domain experts.

Get verifiable, evidence-based answers in seconds

Delivering deeper evidence, greater transparency, and improved usability

ClinicalKey AI has evolved to meet the demands of modern clinical practice with unrivaled full-text knowledge base and technology upgrades — to surface the latest evidence at the point of care.

Natural language queries enable you to ask questions in a conversational way that allows for follow-up questions

Answers are backed by clear citations to published research, allowing for traceability via direct links to help keep your reasoning grounded in peer-reviewed evidence

Responses can be tailored to consider patient context such as age, comorbidities and current medications, when prompted

Share responses and manage query history in a privacy panel

Watch now 2:10 minutes

More guidelines, more journals, more depth—right when you need it

ClinicalKey AI now offers the broadest collection of trusted medical evidence in a clinical AI solution, ensuring answers are not only fast, but firmly grounded in the latest evidence.

More clinical practice guidelines from leading medical societies, including ACC, AACE, CHEST, ACEP, AGA and more

Doubled volume of full‑text journal coverage, featuring titles such as The Lancet family of journals, CHEST, Journal of Allergy and Clinical Immunology, Journal of Thoracic Oncology, and AJOG

Best-in-class medical books, including Braunwald’s Heart Disease, Nelson Textbook of Pediatrics, Sabiston Textbook of Surgery and more
Expanded sources beyond Elsevier, including the New England Journal of Medicine and cross-specialty abstracts from 1,100+ journals

Confidence in AI through traceability and transparency

Instead of searching the open web, ClinicalKey AI is built with a clinician-in-the-loop approach and real-time evidence verification, bringing unprecedented clarity to AI-generated clinical responses.

Real-time citation validation making it easy to confirm evidence instantly

100+ clinicians regularly review and test responses to help keep answers accurate and clinically relevant

Query assistance reframes close‑ended questions to mitigate anchor bias and improve precision

Direct traceability from every answer to the primary source, down to the exact paragraph

A more intuitive, flexible point-of-care experience

The updated ClinicalKey AI interface improves usability and personalization—whether at the bedside or on the go.

Streamlined navigation with a more intuitive layout for faster answer retrieval

Native voice-to-text dictation in the mobile app for hands-free querying

New privacy panel to manage query history with greater control

Population toggle to switch between adult and pediatric perspectives

Share answers with your colleagues and earn CME credits while you work

Turn your everyday clinical questions into collaboration moments and ongoing professional growth. No extra forms. No after-hours effort.

New share feature allows you to easily send ClinicalKey AI conversations to other medical professionals, even if they don’t have an account

Get 0.5 CME credits for every ClinicalKey AI response you review

Check your dashboard anytime to see exactly how many credits you’ve earned

Batch-claim credits whenever you’re ready and submit them directly toward Maintenance of Certification (MOC) for boards like ABIM

Delivering deeper evidence, greater transparency, and improved usability

ClinicalKey AI has evolved to meet the demands of modern clinical practice with unrivaled full-text knowledge base and technology upgrades — to surface the latest evidence at the point of care.

Natural language queries enable you to ask questions in a conversational way that allows for follow-up questions

Answers are backed by clear citations to published research, allowing for traceability via direct links to help keep your reasoning grounded in peer-reviewed evidence

Responses can be tailored to consider patient context such as age, comorbidities and current medications, when prompted

Share responses and manage query history in a privacy panel

Watch now 2:10 minutes

Clinical AI you can trust with your data

ClinicalKey AI is built on Elsevier's commitment to responsible AI — which means your professional data is never used against your interests.

Your clinical search history, specialty, and viewing behaviour are not used to personalise ads or sponsored content — on or off the platform

Your professional identifiers are not shared with advertising networks, identity partners, or third-party data ecosystems

Your usage is not aggregated or shared with sponsors, partners, or third parties for commercial analytics or market intelligence

Confidence in AI through traceability and transparency

Real-time citation validation making it easy to confirm evidence instantly

100+ clinicians regularly review and test responses to help keep answers accurate and clinically relevant

Query assistance reframes close‑ended questions to mitigate anchor bias and improve precision

Direct traceability from every answer to the primary source, down to the exact paragraph

More guidelines, more journals, more depth—right when you need it

ClinicalKey AI now offers the broadest collection of trusted medical evidence in a clinical AI solution, ensuring answers are not only fast, but firmly grounded in the latest evidence.

Guidelines from leading US and international medical societies, including ACC, AACE, CHEST, ACEP, AGA and more 
Doubled volume of full‑text journal coverage, featuring titles such as The Lancet family of journals, CHEST, Journal of Allergy and Clinical Immunology, Journal of Thoracic Oncology, and AJOG 
Best-in-class medical books, including Braunwald’s Heart Disease, Nelson Textbook of Pediatrics, Sabiston Textbook of Surgery and more 
Expanded sources beyond Elsevier, including the New England Journal of Medicine and cross-specialty abstracts from 1,100+ journals

Share answers with your colleagues and earn CME credits while you work

Turn your everyday clinical questions into collaboration moments and ongoing professional growth. No extra forms. No after-hours effort.

Share any ClinicalKey AI response with colleagues directly from the platform, even if they don't have an account — useful for ward rounds, case discussions, and MDT prep

Get 0.5 CME credits for every ClinicalKey AI response you review

Check your dashboard anytime to see exactly how many credits you’ve earned

Batch-claim credits whenever you’re ready and submit them directly toward Maintenance of Certification (MOC) for boards like ABIM

Content Sources

The list of content sources used by ClinicalKey AI will grow over time.*

Elsevier’s proprietary ClinicalKey point of care content

- Clinical Overviews
- Drug Monographs
- Drug Class Overviews
Full text journal articles including the Clinics series
Abstracts from a curated set of journals and copyright-cleared for use
- NEJM, BMJ, JAMA, and other non-Elsevier journals
- The Lancet and other Elsevier journals
Selected US government publications from the FDA, CDC and NLM
Guidelines from the American College of Cardiology (ACC)

Medical reference texts

Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine, 12th Ed.
Goldman-Cecil Medicine, 27th Ed.
Nelson Textbook of Pediatrics, 22nd Ed.
Fanaroff and Martin's Neonatal-Perinatal Medicine, 12th Ed.
Fuhrman and Zimmerman's Pediatric Critical Care, 6th Ed.
Rosen's Emergency Medicine: Concepts & Clinical Practice, 10th Ed.
Williams Textbook of Endocrinology, 15th Ed.
Gabbe's Obstetrics: Normal and Problem Pregnancies, 8th Ed.
Firestein & Kelley's Textbook of Rheumatology, 12th Ed.
Massachusetts General Hospital Comprehensive Clinical Psychiatry, 3rd Ed.
Miller's Anesthesia, 10th Ed.

*The system is updated when new articles from these sources are published and when authors update existing content. Clinical regulations and practices may vary by country. Some included clinical content, such as drug information and guidelines, may not align with regulations and practices outside of the United States.

ClinicalKey AI on the App Store

2025 MedTech Breakthrough Award for AI Innovation

ClinicalKey AI was recognized for:

Expanded access to over 50 countries, bringing generative AI-enabled clinical decision-making worldwide.
New features for embedding ClinicalKey into clinical workflows, including a hybrid app and Epic SSO.
Added continuing medical education and board submission tools to support ongoing learning.
Broader content coverage, now including guidelines and full-text articles such as those from the American College of Cardiology.

ClinicalKey AI

World class clinical information meets artificial intelligence

Black Friday Sale! Save 40% with discount code BFC30.

Try it Free for 14 Days.

For Clinicians

For Residents

ClinicalKey AI

Ask. Explore. Help elevate patient care.

With unrivaled full-text knowledge base and technology upgrades to help you make clinical decisions with confidence. Save 30% with discount code NXGEN30.

For Clinicians

Free for Students

ClinicalKey AI

Ask. Explore. Help elevate
patient care

Traceable, evidence-based answers at the point of care using leading full-text content from

Elsevier and its partners.

Ask. Explore.
Help elevate
patient care

Traceable, evidence-based answers at the

point of care using leading full-text content

from Elsevier and its partners.

ClinicalKey AI is a clinical decision support solution that aids clinicians by combining trusted, evidence-based clinical content with generative AI to transform complexity into clarity

Transform Complexity into Clarity

With ClinicalKey AI, clinicians can ask questions in a conversational format with AI technology that allows for natural language queries getting an answer in a fraction of the time.

Base decisions on summarized information delivered in bulleted fashion and backed by citations.
Account for patient complexity - including multiple comorbidities and medications - when prompted.
Help strengthen confidence through trusted quality information by accessing evidence-based content curated by Elsevier's expansive network of domain experts.

Transform Complexity into Clarity

With ClinicalKey AI, clinicians can ask questions in a conversational format with AI technology that allows for natural language queries getting an answer in a fraction of the time.

Base decisions on summarized information delivered in bulleted fashion and backed by citations.
Account for patient complexity - including multiple comorbidities and medications - when prompted.
Help strengthen confidence through trusted quality information by accessing evidence-based content curated by Elsevier's expansive network of domain experts.

Get verifiable, evidence-based answers in seconds

Delivering deeper evidence, greater transparency, and improved usability

ClinicalKey AI has evolved to meet the demands of modern clinical practice with unrivaled full-text knowledge base and technology upgrades — to surface the latest evidence at the point of care.

Natural language queries enable you to ask questions in a conversational way that allows for follow-up questions

Answers are backed by clear citations to published research, allowing for traceability via direct links to help keep your reasoning grounded in peer-reviewed evidence

Responses can be tailored to consider patient context such as age, comorbidities and current medications, when prompted

Share responses and manage query history in a privacy panel

Watch now 2:10 minutes

More guidelines, more journals, more depth—right when you need it

ClinicalKey AI now offers the broadest collection of trusted medical evidence in a clinical AI solution, ensuring answers are not only fast, but firmly grounded in the latest evidence.

More clinical practice guidelines from leading medical societies, including ACC, AACE, CHEST, ACEP, AGA and more

Doubled volume of full‑text journal coverage, featuring titles such as The Lancet family of journals, CHEST, Journal of Allergy and Clinical Immunology, Journal of Thoracic Oncology, and AJOG

Best-in-class medical books, including Braunwald’s Heart Disease, Nelson Textbook of Pediatrics, Sabiston Textbook of Surgery and more
Expanded sources beyond Elsevier, including the New England Journal of Medicine and cross-specialty abstracts from 1,100+ journals

Confidence in AI through traceability and transparency

Real-time citation validation making it easy to confirm evidence instantly

100+ clinicians regularly review and test responses to help keep answers accurate and clinically relevant

Query assistance reframes close‑ended questions to mitigate anchor bias and improve precision

Direct traceability from every answer to the primary source, down to the exact paragraph

A more intuitive, flexible point-of-care experience

The updated ClinicalKey AI interface improves usability and personalization—whether at the bedside or on the go.

Streamlined navigation with a more intuitive layout for faster answer retrieval

Native voice-to-text dictation in the mobile app for hands-free querying

New privacy panel to manage query history with greater control

Population toggle to switch between adult and pediatric perspectives

Share answers with your colleagues and earn CME credits while you work

Turn your everyday clinical questions into collaboration moments and ongoing professional growth. No extra forms. No after-hours effort.

New share feature allows you to easily send ClinicalKey AI conversations to other medical professionals, even if they don’t have an account

Get 0.5 CME credits for every ClinicalKey AI response you review

Check your dashboard anytime to see exactly how many credits you’ve earned

Batch-claim credits whenever you’re ready and submit them directly toward Maintenance of Certification (MOC) for boards like ABIM

Delivering deeper evidence, greater transparency, and improved usability

ClinicalKey AI has evolved to meet the demands of modern clinical practice with unrivaled full-text knowledge base and technology upgrades — to surface the latest evidence at the point of care.

Natural language queries enable you to ask questions in a conversational way that allows for follow-up questions

Answers are backed by clear citations to published research, allowing for traceability via direct links to help keep your reasoning grounded in peer-reviewed evidence

Responses can be tailored to consider patient context such as age, comorbidities and current medications, when prompted

Share responses and manage query history in a privacy panel

Watch now 2:10 minutes

Clinical AI you can trust with your data

ClinicalKey AI is built on Elsevier's commitment to responsible AI — which means your professional data is never used against your interests.

Your clinical search history, specialty, and viewing behaviour are not used to personalise ads or sponsored content — on or off the platform

Your professional identifiers are not shared with advertising networks, identity partners, or third-party data ecosystems

Your usage is not aggregated or shared with sponsors, partners, or third parties for commercial analytics or market intelligence

Confidence in AI through traceability and transparency

Real-time citation validation making it easy to confirm evidence instantly

100+ clinicians regularly review and test responses to help keep answers accurate and clinically relevant

Query assistance reframes close‑ended questions to mitigate anchor bias and improve precision

Direct traceability from every answer to the primary source, down to the exact paragraph

More guidelines, more journals, more depth—right when you need it

ClinicalKey AI now offers the broadest collection of trusted medical evidence in a clinical AI solution, ensuring answers are not only fast, but firmly grounded in the latest evidence.

Guidelines from leading US and international medical societies, including ACC, AACE, CHEST, ACEP, AGA and more 
Doubled volume of full‑text journal coverage, featuring titles such as The Lancet family of journals, CHEST, Journal of Allergy and Clinical Immunology, Journal of Thoracic Oncology, and AJOG 
Best-in-class medical books, including Braunwald’s Heart Disease, Nelson Textbook of Pediatrics, Sabiston Textbook of Surgery and more 
Expanded sources beyond Elsevier, including the New England Journal of Medicine and cross-specialty abstracts from 1,100+ journals

Share answers with your colleagues and earn CME credits while you work

Turn your everyday clinical questions into collaboration moments and ongoing professional growth. No extra forms. No after-hours effort.

Share any ClinicalKey AI response with colleagues directly from the platform, even if they don't have an account — useful for ward rounds, case discussions, and MDT prep

Get 0.5 CME credits for every ClinicalKey AI response you review

Check your dashboard anytime to see exactly how many credits you’ve earned

Batch-claim credits whenever you’re ready and submit them directly toward Maintenance of Certification (MOC) for boards like ABIM

Choose your plan

90-day free trial on individual plans. Free for eligible medical students*

Available countries

Annual

INDIVIDUAL

Trusted evidence from leading journals, books, and clinical references
Responsible AI built for healthcare
CME and MOC credits to select boards
Shareable answers and collaboration-ready outputs

Best value

US $349 / year

$0.96 / day. Billed annually

90 days free, then $349/year

Monthly

INDIVIDUAL

Same evidence-backed responsible AI, month to month
Cancel at any time
Upgrade to annual and save 25%

No commitment

US $39 / month

$1.28 / day. Billed monthly

90 days free, then $39/month

Clinical access

MEDICAL STUDENT

Free for medical students in the USA & Canada. No credit card required
Fast answers for busy clinical rotations
Spend less time searching, more time learning
Access activates immediately

Free for one year

US $0

*Only available to medical students in the USA & Canada with a valid medical school email address

Authors: Ron Walls + 3 more

Content sources

The list of content sources used by ClinicalKey AI will grow over time.*

Elsevier’s proprietary ClinicalKey point of care content
- Clinical Overviews
- Drug Monographs
- Drug Class Overviews
Full text journal articles including the Clinics series
Abstracts from a curated set of journals and copyright-cleared for use
- NEJM, BMJ, JAMA, and other non-Elsevier journals
- The Lancet and other Elsevier journal

Medical reference texts
- Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine, 12th Ed.
- Goldman-Cecil Medicine, 27th Ed.
- Nelson Textbook of Pediatrics, 22nd Ed.
- Fanaroff and Martin's Neonatal-Perinatal Medicine, 12th Ed.
- Fuhrman and Zimmerman's Pediatric Critical Care, 6th Ed.
- Rosen's Emergency Medicine: Concepts & Clinical Practice, 10th Ed.
- Williams Textbook of Endocrinology, 15th Ed.

Surface the knowledge you need, in less time

Accountability through human oversight 100 + clinicians regularly review and test responses to help keep answers accurate and clinically relevant.

Answers grounded in real evidence 1000 + content sources, get answers from Elsevier and non-Elsevier journals, clinical overviews, drug monographs and other evidence-based sources.

Responsible AI made for healthcare 98.6% comprehension designed with the clinician in mind, ClinicalKey AI understands clinical queries, from shorthand to medical acronyms and underlying clinical intent to provide relevant responses.

2025 MedTech Breakthrough Award for AI Innovation

C2x winner of the MedTech Breakthrough Award for AI Innovation

ClinicalKey AI was recognized for:

Expanded access to over 50 countries to make generative AI-enabled clinical decision-making available across the world.
New functionality to allow ClinicalKey to be embedded into the clinical workflow, including a hybrid app and SSO through Epic.
Continuing medical education and board submission features to support ongoing education that’s essential in healthcare.
Expanded content coverage with guidelines and full-text journal articles, including practice guidelines from the American College of Cardiology.

ClinicalKey AI

Ask. Explore. Help elevate patient care.

Ask. Explore. Help elevate patient care

Ask. Explore.Help elevate patient care

ClinicalKey AI combines trusted, evidence-based clinical content with conversational search powered by generative AI to support clinicians in delivering high-quality patient care. ​

Transform Complexity into Clarity

Transform Complexity into Clarity

Get verifiable, evidence-based answers in seconds

Delivering deeper evidence, greater transparency, and improved usability

More guidelines, more journals, more depth—right when you need it

Confidence in AI through traceability and transparency

A more intuitive, flexible point-of-care experience

Share answers with your colleagues and earn CME credits while you work

Delivering deeper evidence, greater transparency, and improved usability

Clinical AI you can trust with your data

Confidence in AI through traceability and transparency

More guidelines, more journals, more depth—right when you need it

Share answers with your colleagues and earn CME credits while you work

Get ClinicalKey AI on the app store

2025 MedTech Breakthrough Award for AI Innovation

ClinicalKey AI - Powered by our vast library of leading evidence-based content

Try ClinicalKey AI risk free for 14 days

Experience ClinicalKey AI free for 14 days

Experience ClinicalKey AI

ClinicalKey AI

Ask. Explore. Help elevate patient care.

Ask. Explore. Help elevate patient care

Ask. Explore.Help elevate patient care

ClinicalKey AI is a clinical decision support solution that aids clinicians by combining trusted, evidence-based clinical content with generative AI to transform complexity into clarity

Transform Complexity into Clarity

Transform Complexity into Clarity

Get verifiable, evidence-based answers in seconds

Delivering deeper evidence, greater transparency, and improved usability

More guidelines, more journals, more depth—right when you need it

Confidence in AI through traceability and transparency

A more intuitive, flexible point-of-care experience

Share answers with your colleagues and earn CME credits while you work

Delivering deeper evidence, greater transparency, and improved usability

Clinical AI you can trust with your data

Confidence in AI through traceability and transparency

More guidelines, more journals, more depth—right when you need it

Share answers with your colleagues and earn CME credits while you work

Choose your plan

Available countries

Annual

Monthly

Clinical access

Powered by world-class content from Elsevier and its partners

The Lancet

JACC

The New England Journal of Medicine

Braunwald's Heart Disease

Sabiston Textbook of Surgery

Nelson Textbook of Pediatrics

CHEST

JACI

Journal of Thoracic Oncology

AJOG

Roberts and Hedges’ Clinical Procedures in Emergency Medicine and Acute Care

Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases

Miller's Anesthesia

Goldman Cecil Medicine

Rosen's Emergency Medicine: Concepts and Clinical Practice

Brenner and Rector's The Kidney

Gabbe's Obstetrics: Normal and Problem Pregnancies

Kanski's Clinical Ophthalmology

Avery's Diseases of the Newborn

Pediatric Gastrointestinal and Liver Disease

Massachusetts General Hospital Comprehensive Clinical Psychiatry

Firestein & Kelley’s Textbook of Rheumatology

Current Surgical Therapy

Campbell-Walsh-Wein Urology

Braunwald's Heart Disease

Goldman Cecil Medicine

Nelson Textbook of Pediatrics

JACC

The Lancet

Rosen's Emergency Medicine: Concepts and Clinical Practice

Content sources

The list of content sources used by ClinicalKey AI will grow over time.* ​​

Ask. Explore. Help elevate
patient care

Ask. Explore.
Help elevate
patient care

ClinicalKey AI combines trusted, evidence-based clinical content with conversational search powered by generative AI to support clinicians in delivering high-quality patient care.

Ask. Explore. Help elevate
patient care

Ask. Explore.
Help elevate
patient care

The list of content sources used by ClinicalKey AI will grow over time.*