ClinicalKey AI

World class clinical information meets artificial intelligence

Black Friday Sale! Save 40% with discount code BFC30.

Try it Free for 14 Days.

Individual subscriptions are available in the US, Canada, UK, Australia, New Zealand, Germany, India, Cyprus, Latvia, Greece, Malta, Bulgaria, Qatar, and Bahrain. For other countries, please register your interest here, and we'll notify you as soon as it becomes available in your region.

Click here to see available countries

ClinicalKey AI

Ask. Explore. Help elevate patient care.

ClinicalKey AIClinicalKey AI

ClinicalKey AI combines trusted, evidence-based clinical content with conversational search powered by generative AI to support clinicians in delivering high-quality patient care. ​

Transform Complexity into Clarity

With ClinicalKey AI, clinicians can ask questions in a conversational format with AI technology that allows for natural language queries getting an answer in a fraction of the time.

  • Base decisions on summarized information delivered in bulleted fashion and backed by citations.
  • Account for patient complexity - including multiple comorbidities and medications - when prompted.
  • Help strengthen confidence through trusted quality information by accessing evidence-based content curated by Elsevier's expansive network of domain experts.

Transform Complexity into Clarity

With ClinicalKey AI, clinicians can ask questions in a conversational format with AI technology that allows for natural language queries getting an answer in a fraction of the time.

  • Base decisions on summarized information delivered in bulleted fashion and backed by citations.
  • Account for patient complexity - including multiple comorbidities and medications - when prompted.
  • Help strengthen confidence through trusted quality information by accessing evidence-based content curated by Elsevier's expansive network of domain experts.

Transform complexity into clarity

Ask questions in a conversational way

ClinicalKey AI allows for natural language queries, so you can ask clinical questions in a conversational way and get summarized evidence in a bulleted format. 

  • Answers are backed by citations to published research to help keep your reasoning grounded in peer-reviewed evidence
  • Go deeper by asking follow-up questions to your initial query
  • Queries are saved so you can revisit them at any time 

At the speed of rounds

Whether you’re on clinical rotations or practicing full-time, every moment matters, and sometimes questions arise that need immediate answers. 

  • Ask ClinicalKey AI to check facts, review complex cases, confirm management plans, or clarify unfamiliar medications 
  • Responses consider patient context when prompted 
  • Quickly confirm which findings align with the data — without endless cross-checking 

Most AI tools weren’t built for healthcare

They produce confident answers without the clinical guardrails healthcare demands — introducing risk where reliability should come first. Instead of searching the open web, ClinicalKey AI: 

  • Pulls exclusively from peer-reviewed journals, clinical reference texts, and authoritative guidelines, refreshed daily 
  • Provides linked references, making it easy to confirm evidence instantly 
  • Has 100+ clinicians regularly review and test responses to help keep answers accurate and clinically relevant

Earn CME credits while you work

Turn your everyday clinical questions into ongoing professional growth. No extra forms. No after-hours effort. 

  • Get 0.5 CME credits for every ClinicalKey AI response you review 
  • Check your dashboard anytime to see exactly how many credits you’ve earned 
  • Batch-claim credits whenever you’re ready  and submit them directly toward Maintenance of Certification (MOC) for boards like ABIM 

More than just quick summaries and abstracts

  • Move beyond surface-level insights to explore the full depth of clinical knowledge  

  • Connect directly to the complete, authoritative evidence behind every answer  

  • Seamless access to full-text books, journal articles, and trusted reference works  


Content Sources

The list of content sources used by ClinicalKey AI will grow over time.* 

 
  • Elsevier’s proprietary ClinicalKey point of care content
    • Clinical Overviews

    • Drug Monographs

    • Drug Class Overviews

  • Full text journal articles including the Clinics series

  • Abstracts from a curated set of journals and copyright-cleared for use

    • NEJM, BMJ, JAMA, and other non-Elsevier journals

    • The Lancet and other Elsevier journals

  • Selected US government publications from the FDA, CDC and NLM

  • Guidelines from the American College of Cardiology (ACC)

Medical reference texts

  • Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine, 12th Ed.

  • Goldman-Cecil Medicine, 27th Ed.

  • Nelson Textbook of Pediatrics, 22nd Ed.

  • Fanaroff and Martin's Neonatal-Perinatal Medicine, 12th Ed.

  • Fuhrman and Zimmerman's Pediatric Critical Care, 6th Ed.

  • Rosen's Emergency Medicine: Concepts & Clinical Practice, 10th Ed.

  • Williams Textbook of Endocrinology, 15th Ed.

  • Gabbe's Obstetrics: Normal and Problem Pregnancies, 8th Ed.

  • Firestein & Kelley's Textbook of Rheumatology, 12th Ed.

  • Massachusetts General Hospital Comprehensive Clinical Psychiatry, 3rd Ed.

  • Miller's Anesthesia, 10th Ed.

*The system is updated when new articles from these sources are published and when authors update existing content. Clinical regulations and practices may vary by country. Some included clinical content, such as drug information and guidelines, may not align with regulations and practices outside of the United States.


ClinicalKey AI on the App Store

An existing subscription to ClinicalKey AI is required to use this mobile app.

App StoreApp Store
Google PlayGoogle Play

Get ClinicalKey AI on the app store

An existing subscription to ClinicalKey AI is required to use this mobile app.


2025 MedTech Breakthrough Award for AI Innovation

ClinicalKey AI was recognized for:

  • Expanded access to over 50 countries, bringing generative AI-enabled clinical decision-making worldwide.
  • New features for embedding ClinicalKey into clinical workflows, including a hybrid app and Epic SSO.
  • Added continuing medical education and board submission tools to support ongoing learning.
  • Broader content coverage, now including guidelines and full-text articles such as those from the American College of Cardiology.


CKAI - Powered by our vast library of leading evidence-based contentCKAI - Powered by our vast library of leading evidence-based content

ClinicalKey AI - Powered by our vast library of leading evidence-based content


Try ClinicalKey AI risk free for 14 days

Your free trial will convert to a paid subscription after 14 days and renews automatically. You can cancel your trial at any time.

Experience ClinicalKey AI free for 14 days

Try it today and see the difference.

ClinicalKey AI

World class clinical information meets artificial intelligence

Black Friday Sale! Save 40% with discount code BFC30.

Try it Free for 14 Days.

Individual subscriptions are available in the US, Canada, UK, Australia, New Zealand, Germany, India, Cyprus, Latvia, Greece, Malta, Bulgaria, Qatar, and Bahrain. For other countries, please register your interest here, and we'll notify you as soon as it becomes available in your region.

Click here to see available countries

ClinicalKey AI

Ask. Explore. Help elevate patient care.

ClinicalKey AIClinicalKey AI

ClinicalKey AI is a clinical decision support solution that aids clinicians by combining trusted, evidence-based clinical content with generative AI to transform complexity into clarity

Transform Complexity into Clarity

With ClinicalKey AI, clinicians can ask questions in a conversational format with AI technology that allows for natural language queries getting an answer in a fraction of the time.

  • Base decisions on summarized information delivered in bulleted fashion and backed by citations.
  • Account for patient complexity - including multiple comorbidities and medications - when prompted.
  • Help strengthen confidence through trusted quality information by accessing evidence-based content curated by Elsevier's expansive network of domain experts.

Transform Complexity into Clarity

With ClinicalKey AI, clinicians can ask questions in a conversational format with AI technology that allows for natural language queries getting an answer in a fraction of the time.

  • Base decisions on summarized information delivered in bulleted fashion and backed by citations.
  • Account for patient complexity - including multiple comorbidities and medications - when prompted.
  • Help strengthen confidence through trusted quality information by accessing evidence-based content curated by Elsevier's expansive network of domain experts.

Transform complexity into clarity

Ask questions in a conversational way

ClinicalKey AI allows for natural language queries, so you can ask clinical questions in a conversational way and get summarized evidence in a bulleted format. 

  • Answers are backed by citations to published research to help keep your reasoning grounded in peer-reviewed evidence
  • Go deeper by asking follow-up questions to your initial query
  • Queries are saved so you can revisit them at any time 

At the speed of rounds

Whether you’re on clinical rotations or practicing full-time, every moment matters, and sometimes questions arise that need immediate answers. 

  • Ask ClinicalKey AI to check facts, review complex cases, confirm management plans, or clarify unfamiliar medications 
  • Responses consider patient context when prompted 
  • Quickly confirm which findings align with the data — without endless cross-checking 

Most AI tools weren’t built for healthcare

They produce confident answers without the clinical guardrails healthcare demands — introducing risk where reliability should come first. Instead of searching the open web, ClinicalKey AI: 

  • Pulls exclusively from peer-reviewed journals, clinical reference texts, and authoritative guidelines, refreshed daily 
  • Provides linked references, making it easy to confirm evidence instantly 
  • Has 100+ clinicians regularly review and test responses to help keep answers accurate and clinically relevant

Earn CME credits while you work

Turn your everyday clinical questions into ongoing professional growth. No extra forms. No after-hours effort. 

  • Get 0.5 CME credits for every ClinicalKey AI response you review 
  • Check your dashboard anytime to see exactly how many credits you’ve earned 
  • Batch-claim credits whenever you’re ready  and submit them directly toward Maintenance of Certification (MOC) for boards like ABIM 

More than just quick summaries and abstracts

  • Move beyond surface-level insights to explore the full depth of clinical knowledge  

  • Connect directly to the complete, authoritative evidence behind every answer  

  • Seamless access to full-text books, journal articles, and trusted reference works  

Powered by world-class content from Elsevier and its partners

Content sources

The list of content sources used by ClinicalKey AI will grow over time.* ​​

  • Elsevier’s proprietary ClinicalKey point of care content

    • Clinical Overviews

    • Drug Monographs

    • Drug Class Overviews

  • Full text journal articles including the Clinics series

  • Abstracts from a curated set of journals and copyright-cleared for use

    • NEJM, BMJ, JAMA, and other non-Elsevier journals

    • The Lancet and other Elsevier journal

  • Medical reference texts

    • Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine, 12th Ed.
    • Goldman-Cecil Medicine, 27th Ed.
    • Nelson Textbook of Pediatrics, 22nd Ed.
    • Fanaroff and Martin's Neonatal-Perinatal Medicine, 12th Ed.
    • Fuhrman and Zimmerman's Pediatric Critical Care, 6th Ed.
    • Rosen's Emergency Medicine: Concepts & Clinical Practice, 10th Ed.
    • Williams Textbook of Endocrinology, 15th Ed.

*The system is updated when new articles from these sources are published and when authors update existing content. Clinical regulations and practices may vary by country. Some included clinical content, such as drug information and guidelines, may not align with regulations and practices outside of the United States.

Surface the knowledge you need, in less time 

Accountability through human oversight 100 + clinicians regularly review and test responses to help keep answers accurate and clinically relevant. Accountability through human oversight 100 + clinicians regularly review and test responses to help keep answers accurate and clinically relevant. 
Answers grounded in real evidence 1000 + content sources, get  answers from Elsevier and non-Elsevier journals, clinical overviews, drug monographs and other evidence-based sources. Answers grounded in real evidence 1000 + content sources, get  answers from Elsevier and non-Elsevier journals, clinical overviews, drug monographs and other evidence-based sources. 
Responsible AI made for healthcare 98.6% comprehension designed with the clinician in mind, ClinicalKey AI understands clinical queries, from shorthand to medical acronyms and underlying clinical intent to provide relevant responses. Responsible AI made for healthcare 98.6% comprehension designed with the clinician in mind, ClinicalKey AI understands clinical queries, from shorthand to medical acronyms and underlying clinical intent to provide relevant responses. 
Expanded global access 50 + countries trusted by clinicians worldwide, ClinicalKey AI is built to support you in clinical decision making, not replace you. Expanded global access 50 + countries trusted by clinicians worldwide, ClinicalKey AI is built to support you in clinical decision making, not replace you.

Try ClinicalKey AI risk free for 14 days

Your free trial will convert to a paid subscription after 14 days and renews automatically. You can cancel your trial at any time.

Experience ClinicalKey AI free for 14 days

Try it today and see the difference.

An existing subscription to ClinicalKey AI is required to use this mobile app.

App StoreApp Store
Google PlayGoogle Play

Get ClinicalKey AI on the app store

An existing subscription to ClinicalKey AI is required to use this mobile app.

2025 MedTech Breakthrough Award for AI Innovation

C2x winner of the MedTech Breakthrough Award for AI Innovation

ClinicalKey AI was recognized for:

  • Expanded access to over 50 countries to make generative AI-enabled clinical decision-making available across the world.
  • New functionality to allow ClinicalKey to be embedded into the clinical workflow, including a hybrid app and SSO through Epic.
  • Continuing medical education and board submission features to support ongoing education that’s essential in healthcare.
  • Expanded content coverage with guidelines and full-text journal articles, including practice guidelines from the American College of Cardiology.